Nutrient-sensing mTOR-mediated pathway regulates leptin production in isolated rat adipocytes
نویسندگان
چکیده
منابع مشابه
Nutrient-sensing mTOR-mediated pathway regulates leptin production in isolated rat adipocytes.
Leptin biosynthesis in adipose cells in vivo is increased by food intake and decreased by food deprivation. However, the mechanism that couples leptin production to food intake remains unknown. We found that addition of leucine to isolated rat adipocytes significantly increased leptin production by these cells, suggesting that postprandial leptin levels may be directly regulated by dietary leuc...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Endocrinology and Metabolism
سال: 2003
ISSN: 0193-1849,1522-1555
DOI: 10.1152/ajpendo.00230.2002